MGMED has the Korean BAC library and manufactures microarrays based on clones containing key genes. MGMED produces Array Comparative Genomic Hybridization (CGH), allowing for greater resolution than traditional CGH. MGMED also developed an analytical software package for accurate and quick data evaluation.
MG med currently produces 6 types of CHIP products. Chip types include:
P-Chip: Screen chromosomal aneuploidy in fertilized eggs to increase success rates of in vitro fertilization
M-Chip and N-Chip: Screen chromosomal abnormalities of fetus
G-Chip: Screen chromosomal abnormalities in children and adults
C-Chip: Screen chromosomal abnormalities in cancer cells
S-chip: Screen chromosomal abnormalities in stem cells
2. array CGH
MGMED produces array comparative genomic hybridization (CGH) array to detect chromosomal abnormalities from genomic DNA. MGMED’s microarray has been designed with DNA extracted from major genes of BAC clones. The extracted DNAs are spotted on slides into24 spots using a pin contact method, with three replicates to enhance the stability and resolution. The array slide is typical in size so that it can be scanned by various scanner. MGMED produces microarray chips under the drug production level, the entire production procedures and quality are strictly monitored. All necessary reagents for production are directly produced by MGMED, which gives us to strength for increasing stability and price competitiveness.
3. MG viewer
MGMED developed microarray analyzing software, MG Viewer, for accurate and fast data evaluation.
MG viewer has following features:
Specialized software: Array CGH result report and various options for Array CGH analyses
Use of TIFF images from various scanners: Genepix 4000B (Molecular Devices) scanner or similar
A fully automated analysis system: Final results obtained within 1 minute via one-touch input system. Auto gridding and quantification, set normalization method and Flagging criteria options are saved.
1. BAC clone
MGMED has Korean BAC clone library. Chromosome numbers and sequences were identified using BAC end-sequencing, and then each identified gene sequence was used as probe for fluorescent in situ hybridization (FISH) to verify the position on the genome of each BAC clone. Selected major genes were used for microarray production.
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